How much is a flight from Chicago to Santa Cruz de la Sierra?

There’s no fixed price — fares between Chicago and Santa Cruz can vary a lot by day or time.

Pick a travel date to see today’s available fares.

Flying during the week can be more affordable, as weekend flights tend to be pricier. Also consider demand and availability: the last remaining seats often come at higher fares!

Is there more than one airport in Chicago or Santa Cruz?

Even short-haul routes can benefit from considering secondary airports. It may open up more flight times or cheaper fares.

• Airports in Chicago: Chicago has 3 airports - Midway, O'Hare, Rockford.
• Airports in Santa Cruz: Santa Cruz is another arrival option.

Airports with more daily flights offer more flexibility if plans change or delays occur. If you’re flexible, consider airports near Santa Cruz as well.

Customize your flight from Chicago to Santa Cruz de la Sierra

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from the best airlines and travel agencies.

Other popular destinations

Thinking about Bolivia? You might also consider: Cochabamba, La Paz, Santa Cruz, Sucre, Tarija.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.