What’s the cost of a flight from Knoxville to Panama City?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Knoxville and Panama City.

Choose a date to explore the best fares now.

If possible, avoid holiday periods: ticket prices tend to rise quickly and availability drops, especially on busy routes. Morning and evening flights are often in high demand too — book early to get a good fare.

Best airport options between Knoxville and Panama City

If you're open to flying into or out of more than one airport, you’ll have more routes to compare.

• Airports in Knoxville: Knoxville - McGhee Tyson is the only operating airport.
• Airports in Panama City: In Panama City, 2 airports are available - Pacífico International Airport, Paitilla.

Some airports offer extras like lounges, fast track, or self check-in — good to keep in mind. Comparing airports by services offered helps you balance cost and comfort.

Customize your flight from Knoxville to Panama City

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from the best airlines and travel agencies.

Other popular destinations

Thinking about Panama? You might also consider: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.